Guido Li Volsi
Professor of Physiology
University of Catania

glivolsi@unict.it
Teaching
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Guido Li Volsi is professor of physiology at the University of Catania - I.

He teaches Physiology to students of the Degree in Biological Sciences and Cell Physiology to students of the Master's Degree in Cellular and Molecular Biology.


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Physiology (9 ECTS)

The course aims to investigate issues relating to the basic mechanisms of animal cell including the interaction with other cells.
General iformation about organs and system are given.


Topics

The cell membrane
Exchanges between cells and environment: Permeability of the membranes -  diffusion in the
lipidic matrix - Ion channels - Osmosis - mediated transport (facilitated diffusion) - Transport passive and active primary and secondary - Mediated by transport vesicles.

Transmembrane ion fluxes and
membrane potential electrical properties
Ionic Equilibria
Electrochemical Potential
Genesis and maintenance of
membrane potential

Excitable cells
Gated ion channels - Genesis and conduction of action potential in nerve cells and
muscle - Refractory - Accommodation - Speed of conduction and myelination - Basics of ionic potential in myocardial fibers - the contractile mechanism of skeletal
and smooth muscle fibers - Ca2+ ions in muscle contraction - Excitation-contraction coupling

Intercellular communication
Communication mechanisms (autocrine, paracrine, endocrine) - Local Messengers - Membrane Receptors and intracellular receptor - G protein and second messengers - hormones - synaptic transmission - Synapses: electrical and chemical properties - Exocytosis and Ca2+ - Neurotransmitters and neuromodulators

The coding of sensory information
Receptors (tactile, thermal, proprioceptive, visual, auditory, vestibular, gustatory, olfactory) - The reflex arcs

General information about organs and systems
The digestive function, cardiovascular function, respiratory function - osmoregulation and excretion - Metabolism and temperature - the reproductive function
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Cell Physiology (7 ECTS)


The course aims to investigate issues relating to the operation of animal cell including some mechanisms of interaction with other cells and the interstitium.

Special attention is given to the problems associated with the control of cellular functions, the role of intracellular ion channels in the homeostasis of the environment, both in terms of electro-chemical and physical view. A separate section is concerned to elucidate the mechanisms of growth, regeneration, protection, feedback control.
Finally, we examined the physiological mechanisms in special or extreme conditions.

Topics

General - Physiology of mitochondria - regulation of cell functions through the extracellular calcium
Cellular responses to hormones
Sodium-calcium exchange current
Adjustment of intracellular chloride
Cell volume regulation
Role of glia in the homeostasis of water and ions
The membrane transport in red blood cells
Ion channels in excitable cells
Ion channels in sperm
Ion channels in the egg
Biophysics of the nuclear membrane
Modification of ion channels during development
Chemo-dependent ion channels
Voltage-gated ion channels
Mechano-sensitive ion channels
Stimulus-response coupling in metabolic sensors
Growth Factors
Birth and regeneration of synapses
The protection mechanisms
Control of activities cellular
Hepatocyte physiology
Cellular mechanisms of learning
Effects of high pressure on cellular processes
Effects of ionizing radiations on cellular processes


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